The MURAB project has the ambition to drastically improve precision and effectiveness of the biopsy gathering for cancer diagnostic operations. By reducing the usage of expensive Magnetic Resonance Imaging (MRI) to a minimum in the workflow and at the same time yield the same precision during samples targeting, a new workflow will be offered to the practice. Guided by a novel MRI-Ultrasound (US) registration, a robotically steered US transducer equipped with an acoustically transparent force sensing will autonomously scan the target area and optimally acquire volumetric and elastographic data. An innovative technique, called Tissue Active Slam (TAS), will be developed in the project to optimally register the intraoperational acquired volume to the preoperational MR image